BioQuant Seminars
In this series of seminars, projects that combine biological research with quantitative analysis, modelling and simulation are presented and discussed The seminars are organized in cooperation with BIOMS and the graduate program BIOQUANT. They take place twice monthly in lecture room 041 of the BIOQUANT (Im Neuenheimer Feld 267) at 5 pm.
To receive information about upcoming events on a regular basis, please use the LISTSERV registration form.
Upcoming Talks
| Date | Name Institution | Title | Host | Special |
|---|---|---|---|---|
| 2012-05-22 17:00 | Gaudenz Danuser Harvard Medical School Boston, USA |
Integration of chemical and mechanical signals in cell motility. | U.Schwarz | |
| 2012-06-05 17:00 | Werner Mewes Technische Universität München |
Complexity and causality in basic research and health care. | R.Russell | |
| 2012-06-12 17:00 | Peter Schuster Universität Wien |
What did the molecular connection contribute to an understanding of biological evolution? -- Insights from Watson and Crick to systems biology. | T. Holstein | |
| 2012-06-22 10:00 | Robert Grosse Universität Marburg |
Actin' in different compartments: formins orchestrate SRF transcription. | Roland Eils | 10:00 |
| 2012-06-26 17:00 | Claudia Veigel Ludwig-Maximilians-Universität München |
Myosin motors at the single molecule level. | U.Schwarz, R.Schröder | |
| 2012-07-03 17:00 | Andrei Lupas Max-Planck-Institute for Developmental Biology, Tübingen |
On the origin of folded proteins. | R. Russel | |
| 2012-07-17 17:00 | Edo Kussell Center for Genomics and Systems Biology, New York University |
Single-cell view of bacterial populations in fluctuating environments. | V. Sourjik |
Past Talks
| Date | Name Institution | Title | Host | Special |
|---|---|---|---|---|
| 2012-05-08 17:00 | Martin Howard John Innes Centre Norwich, England |
Dissecting quantitative epigenetic silencing through mathematical modelling and experiments. | T. Höfer | |
| 2012-04-24 17:00 | Huajian Gao Brown University Rhode Isalnd, USA |
Mechanics of cell-materials interaction. | U.Schwarz | |
| 2011-12-13 17:00 | Dimitris Thanos Biomedical Research Foundation, Athens |
Coordination of the human antiviral transcriptional program by stochastic interactions. | T. Höfer | |
| 2011-12-06 17:00 | Paul van der Schoot Technische Universtität, Eindhoven |
Physical regulation of the in vitro assembly of simple viruses. | U. Schwarz | |
| 2011-11-29 17:00 | Philippe Bastiaens Max Planck Institute of Molecular Physiology |
Rules that govern the spatial organisation of Ras signaling. | A. García-Sáez | |
| 2011-11-22 17:00 | Patricia Basserau Institut Curie, Paris |
How proteins and lipids sense membrane curvature. | U. Schwarz | |
| 2011-11-17 17:00 | Gijsje Koenderink AMOLF, Amsterdam |
Myosin motor control of cytosketal organization. | U. Schwarz | |
| 2011-11-15 17:00 | Mike White University of Liverpool |
Dynamics and function of the NF-kB signalling system. | T. Höfer | |
| 2011-10-04 17:00 | Taras V. Pogorelov University of Illinois at Urbana-Champaign |
Membranes as a platform for protein activation: capturing dynamics of lipid bilayers and protein-membrane interactions using the Highly Mobile Membrane Mimetic (HMMM) model. | Rob Russel | |
| 2011-09-06 17:00 | Thomas C. Bishop Louisiana Tech University |
Molecular dynamics studies of nucleosome positioning | J. Langowski | |
| 2011-06-28 17:00 | Andrew B. Goryachev University of Edinburgh |
Autofocusing mechanisms in cellular morphogenesis. | V. Sourjik | Room 043 |
| 2011-06-14 17:00 | Dieter W. Heermann University of Heidelberg |
Chromosomes: Loops and Entropy, that's what it's all about. | V. Sourjik | |
| 2011-06-07 17:00 | Albrecht Ott Universität Saarland |
Hydra axis specification: Cell mechanics, gene expression fluctuations and spontaneous symmetry-breaking. | T. Holstein | Room 042 |
| 2011-05-31 17:00 | Clemens Franz CFN Karlsruhe |
Tailored 2D and 3D cell culture substrates to study cell adhesion and contraction. | U. Schwarz | |
| 2011-05-24 17:00 | Harri Lähdesmäki Aalto University School of Science and Technology, Finland |
Modeling signaling pathway dynamics and high-throughput measurements from heterogeneous samples. | T. Höfer | |
| 2011-05-17 17:00 | Edward Lemke EMBL, Heidelberg |
Single Molecule, Microfluidic and Genetically Encoded Chemical Tools to Study Protein Structure and Dynamics. | U. Schwarz | |
| 2011-04-14 13:00 | Pascal Braun Harvard University, USA |
High-quality interactome maps provide insights into disease, network organization and evolution. | Roland Eils | 13:00 |
| 2011-04-12 17:00 | Peter Uetz Proteros Biostructures, Martinsried/Germany and Gaithersburg, MD/USA |
From protein interaction networks to protein function in bacteria and phage. | Rob Russel | |
| 2011-03-16 10:00 | Claes Gustafsson DNA2.0 Inc, Menlo Park, California |
Maximizing heterologous protein expression through systematic gene design. | Victor Sourjik | 10:00 |
| 2011-02-08 17:00 | Martin Falcke Max-Delbrück-Centrum Berlin |
Modelling lamellipodium dynamics suggests a unifying mechanism for morpho-dynamics and force-velocity relation. | U. Kummer | |
| 2011-02-03 10:00 | Dan Siegal-Gaskins Mathematical Biosciences Institute, Ohio |
Predicting high-resolution and compartmentalized gene expression with time-series data deconvolution. | Victor Sourjik | 10:00 lecture room 043 |
| 2011-02-01 17:00 | Rebecca Wade Heidelberg Institute for Theoretical Studies |
Biomolecular Recognition: Complexity, Competition and Computation. | T. Höfer | |
| 2011-01-25 17:00 | Bela Mulder AMOLF Amsterdam |
Survival of the aligned: self-organisation of the plant microtubule cytoskeleton. | U. Schwarz | |
| 2011-01-18 17:00 | Kees Weijer University of Dundee |
Collective cell migration, a key mechanism of development. | T. Höfer | |
| 2011-01-11 17:00 | Phil Selenko Forschungsinstitut für molekulare Pharmakologie Berlin |
Instant in situ Kinase activity profiling by NMR spectroscopy | T. Höfer | |
| 2010-12-14 17:00 | Rob de Boer University of Utrecht |
Analyzing lymphocyte migration through modeling | T. Höfer | |
| 2010-12-09 11:00 | Justin M O'Sullivan Massey University, Auckland, New Zealand |
Using a jack-hammer to crack a nut: unravelling yeast nuclear structure by sequencing. | J. Langowski | 11:00 |
| 2010-12-07 17:00 | Stephan Grill MPI CBG Dresden |
Active forces and flows for cellular polarization | U. Schwarz | |
| 2010-11-09 17:00 | Dennis Bray University of Cambridge |
Conformational spread: theory and experiment | ||
| 2010-10-26 17:00 | Keiichi Namba Osaka University |
High-resolution cryoEM helical image analysis of macromolecular assemblies | ||
| 2010-10-20 10:30 | Wilfried Weber Universität Freiburg |
Synthetic biology for mammalian cell technology and materials science | 10:30 | |
| 2010-07-20 17:00 | Linda J. Broadbelt Northwestern University, Evanston |
In Silico Discovery and Evaluation of Novel Biochemical Pathways | ||
| 2010-07-20 14:15 | Adélia Sequeira Adélia Sequeira, Instituto Superior Técnico, Lisbon |
3D non-Newtonian FSI modeling and simulations for blood flow in arteries | 14:15 | |
| 2010-07-13 17:00 | Thomas Schmidt Leiden University, Netherlands |
Observation of Cellular Signaling One Molecule at a Time | ||
| 2010-07-06 17:00 | Peter Sorger Harvard Medical School |
Measuring and Modeling Receptor-Mediated Apoptosis in Single Human Cells | ||
| 2010-07-05 09:00 | Yoshie Harada University of Kyoto |
Studies on biomolecules using single-molecule imaging and manipulation techniques | ||
| 2010-06-22 17:00 | Gioacchino Natoli IFOM, Milano |
The epigenome and the control of inflammatory gene expression |
| Date | Name | Title | Special |
|---|---|---|---|
| 08.06.2010 | Benoît Ladoux | Microfabricated substrates: an approach to study how substrate rigidity and topography can affect cell mechanics | |
| 01.06.2010 | Sander J. Tans | Tradeoffs and optimality in the evolution of phenotypic plasticity | |
| 11.05.2010 | Ana Garcia | Regulation of apoptosis by Bcl-2 proteins. A single molecule approach | |
| 04.05.2010 | Yuhai Tu | Information processing in a single cell: E. coli's memory and computation | |
| 27.04.2010 | Michael Lässig | Molecular evolution in fitness land- and seascapes | |
| 20.04.2010 | Matthias Rief | Conformational Mechanics of Single Protein Molecules | |
| 18.03.2010 | Chris Sander | Systems biology of cancer cells | |
| 16.03.2010 | Geneviève Dupont | Spatio-temporal organization of Ca2+ dynamics: a modelling-based approach | |
| 16.03.2010 | Margaret Gardel | Mechanics of Contractile Actomyosin Networks | 3 pm |
| 26.01.2010 | Jörg Stelling | Systems analysis of cellular networks under uncertainty | |
| 19.01.2010 | Albert Goldbeter | The dynamical bases of cellular rhythms: Modeling circadian clocks and the cell cycle | |
| 17.11.2009 | Thorsten Hugel | Single molecule kinetics of yeast Hsp90 | |
| 15.12.2009 | Erwin Frey | Bacterial games: noise and correlations in a spatial population model with cyclic competition | |
| 08.12.2009 | Stefan Klumpp | Global growth-rate dependent effects on gene expression in bacteria | |
| 03.11.2009 | Rob Russell | Adding mechanistic and structural details to cellular networks | |
| 27.10.2009 | Erik van Nimwegen | Comparative genomic inference of bacterial regulatory networks | |
| 13.10.2009 | Karsten Kruse | Dynamics of Min proteins in vivo and in vitro | |
| 08.10.2009 | Antonio Politi | Theoretical model for the active and passive mechanical properties of smooth muscle cells | Thursday |
| 22.09.2009 | Martjin Luisterburg | Heterochromatin Protein 1 is involved in the DNA damage response | |
| 09.09.2009 | Freddie Theodoulou | Transport and targeted protein degradation in the control of lipid metabolism: from Arabidopsis to Adrenoleukodystrophy | |
| 09.07.2009 | Michel Bornens | Control of shape, polarity and division axis by growing cells on adhesive micropattern | Thursday! |
| 07.07.2009 | Martin Ackermann | Individuality in Bacteria: on Aging and Cooperation | |
| 16.06.2009 | Martin Hof | The solvent relaxation technique: hydration and mobility in membranes and enzymes | |
| 12.06.2009 | J. Michael Schurr | A Molecular Interpretation of Thermodynamic Preferential Interaction Coefficients. Applications to BSA, DNA, and Non-Equilibrium Forces. | 4 pm, room 044 |
| 09.06.2009 | Grégoire Altan-Bonnet | Cellular heterogeneity: from molecular nuisance to immunobiological function | |
| 04.06.2009 | Erich Bornberg-Bauer | Computational prediction and analyses of structural and functional transitions in protein evolution | 2 pm |
| 02.06.2009 | Attila Becskei | Bistable epigenetic expression in silenced chromatin | |
| 08.05.2009 | Volker Mehrmann | Modellierung, Simulation, Modellreduktion und robuste Regelung von Deskriptorsystemen mit Unsicherheit | |
| 29.04.2009 | Prof. Dr. David J. Chen | DNA-PKcs Phosphorylation in DNA repair and Hematopoietic Stem Cell Maintainance | 2 pm, Host: Prof. Dr. Roland Eils and Dr. Michaela Reichenzeller |
| 07.04.2009 | Stefan Schuster | Why humans cannot make sugar from fatty acids while plants can - Theoretical pathway analysis of metabolism | |
| 01.04.2009 | Tobias Bollenbach | Non-optimal microbial response to antibiotics underlies drug interactions | |
| 20.03.2009 | Kazufumi Mochizuki | Small RNA-directed DNA elimination in Tetrahymena | |
| 18.03.2009 | Dr. Heiko Schmidt | Reconstructing Trees from Multi-Gene Datasets: Supertrees, Supermatrices and Medium-Level Methods | |
| 17.02.2009 | Katalin Fejes Toth | Genome-wide characterization of the mammalian small RNA transcriptome by high throughput sequencing reveals novel classes of small RNAs | |
| 13.01.2009 | Dr. Thomas Surrey | Mechanism of microtubule plus-end tracking of EB1 and CLIP-170 | |
| 09.12.2008 | Prof. Joachim Rädler | Stochastic aspects in artificial gene transfer and gene expression dynamics | |
| 02.12.2008 | Kai Grunwald | Inter-phase instead of interface - transition from academia to entrepreneurship | Gründer-Team Heidelberg GmbH |
| 11.11.2008 | Prof. Martin Howard | Modelling noisy concentration gradients inside single cells and in development | |
| 28.10.2008 | Prof. Ron Heeren | Mass spectrometric imaging and its applications to proteomics | |
| 14.10.2008 | Dr. Térence Strick | Single Molecule Nanomanipulation | |
| 07.10.2008 | Dr. Oleg Krichevsky | DNA as exemplary polymer | |
| 02.09.2008 | Prof. Krishna Garikipati | Mathematical modelling of solid tumor growth | |
| 05.08.2008 | Prof. Dr. Jai Pal Mittal | Antioxidants-Hype or Reality-Bioquantification studies of antioxidants | |
| 22.07.2008 | Dr. Andrew Goryachev | Dynamics of Cdc42 network embodies a Turing-type mechanism of yeast cell polarity | |
| 08.07.2008 | Dr. Johannes Berg | Out-of-equilibrium dynamics of gene expression | |
| 24.06.2008 | Prof. Yossi Klafter | Levy flights and walks and anomalous diffusion in complex systems | |
| 10.06.2008 | Dr. Charlotte von Gall | The circadian pacemaker matures gradually during ontogenetic development | |
| 05.05.2008 | Prof. Gennady Bocharov | Computational modeling of immune responses | Monday! |
| 29.04.2008 | Prof. Ruedi Aebersold | Systems Biology: network of networks | |
| 15.04.2008 | Dr. Lars Hufnagel | Regulation of Growth during Development: Role of Mechanics | |
| 03.04.2008 | Dr. Mark Bathe | Cytoskeletal actin bundles: From mechanics to dynamics, and back | Thursday! |
| 12.02.2008 | Prof. Luis Serrano | Evolvability of transcription networks | |
| 17.01.2008 | Prof. Marie-France Carlier | A biochemical reconstitution approach of the coordinated actin assembly dynamics in motile and morphogenetic processes | BIOQUANT, Thursday (!), 3 pm |
| 22.01.2008 | Dr. Frauke Graeter | How force can guide protein function: molecular simulations of biological force sensors | |
| 18.12.2007 | Dr. Achillefs Kapanidis | Probing gene-transcription mechanisms using single-molecule fluorescence | |
| 04.12.2007 | Dr. Michael Boutros | Dissecting signaling networks with RNAi | |
| 20.11.2007 | Prof. Sarah Keller | Seeing Spots: Liquid domains in Lipid Membranes | |
| 06.11.2007 | Prof. Berenike Maier | Tuning the DNA import motor of Bacillus subtilis | |
| 23.10.2007 | Dr. Ernst Stelzer | Leaving the coverslip behind: light sheet-based fluorescent microscopy (SPIM) | |
| 24.07.2007 | Prof. Motomu Tanaka | Physical modeling of cellular contacts using soft interfaces | |
| 18.07.2007 | Maya Kahan | DNA-computing for medicine and biology | Location: KIP |
| 03.07.2007 | Prof. Ben Fabry | Mechanics of Cancer Metastasis | |
| 26.06.2007 | Prof. Sean Smith | Theoretical studies of Fluorescent Proteins for Cellular Imaging and Nanoparticles for Gene Delivery | |
| 05.06.2007 | 17 invited speakers | MolTools-DKFZ-BIOQUANT Symposium | |
| 22.05.2007 | Dr. Pieter Rein ten Wolde | The importance of space in gene regulatory networks | |
| 08.05.2007 | Prof. Lucas Pelkmans | Towards systems analysis of virus entry and endocytosis | |
| 20.03.2007 | Prof. Tom Duke | The power of hearing: mechanotransduction in the inner ear | |
| 27.02.2007 | Prof. Christoph Schmidt | Mechanics of protein structures: bacteriophage capsids, actin gels and microtubules | |
| 13.02.2007 | Prof. Benjamin Kaupp | How do sperm find the egg? The mechanism of chemotaxis | |
| 30.01.2007 | Dr. Ana Pombo | Functional organisation of chromosomes in the cell nucleus | |
| 16.01.2007 | Prof. Dr. Fraser A. Armstrong | Hydrogenases: Electrochemical Investigations of the Chemistry of Unusual Metalloenzymes, and Inspirations for Future Energy Technologies | Location: INF 252, HS West (Change!) |
| 19.12.2006 | Prof. Peter Swain | Stochasticity and designs of genetic networks | |
| 05.12.2006 | Prof. Erich Sackmann | Elasticity concept of cell membrane self-assembly and functions | |
| 21.11.2006 | Prof. Ralf Bartenschlager | Dissecting the replication pathways of hepatitis C virus | |
| 24.10.2006 | Dr. Markus Kollmann | Circadian rhythms in bacteria: robustness guides the way towards understanding the clock mechanism | |
| 12.09.2006 | Prof. A. Minton | Nonspecific background interactions in biological media: difference between biochemistry in vitro and in vivo |
Contact: E-Mail (Last update: 06/07/2010)

