Publications

Selected Publications

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• Billmann, M., Chaudhary, V., ElMaghraby, M.F., Fischer, B., Boutros, M. (2017). Widespread Rewiring of Genetic Networks upon Cancer Signaling Pathway Activation. Cell Systems S2405-4712:30485-4.

• Voloshanenko, O., Erdmann, G., Dubash, T.D., Augustin, I., Metzig, M., Moffa, G., Hundsrucker, C., Kerr, G., Sandmann, T., Anchang, B., Demir, K., Boehm, C., Leible, S., Ball, C.R., Glimm, H., Spang, R., Boutros, M. (2013). Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells. Nature Communications 4:2610.

• Laufer, C., Fischer, B., Billmann, M., Huber, W., Boutros, M. (2013). Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping. Nature Methods 10:427–431.

• Gross, J., Chaudhary, V., Bartscherer, K., Boutros, M. (2012). Active Wnt proteins aresecreted on exosomes. Nature Cell Biology 14:1036-45.

• Horn, T., Sandmann, T., Fischer, B., Axelsson, E., Huber, W., Boutros, M. (2011). Mapping of signalling networks through synthetic genetic interaction analysis by RNAi. Nature Methods 8:341-6.

• Boutros M., Ahringer, J. (2008). The art and design of genetic screens: RNA interference. Nature Reviews Genetics 9:554-566.

• Boutros, M., L. Bras, W. Huber. (2006). Analysis of cell-based RNAi screens. Genome Biology 7:R66

• Bartscherer, K., Pelte, N., Ingelfinger, D., Boutros, M. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125:523-33.

• Boutros, M., Kiger, A., Armknecht, S., Kerr, K., Hild, M., Koch, B., Haas, S., HD FlyArray, Paro, R., Perrimon, N. (2004). Genome-wide RNAi Analysis of Cell Growth and Viability in Drosophila. Science 303:832-835.

• Boutros, M., Mihaly, J., Bouwmeester, T., Mlodzik, M. (2000). Signaling specificity by Frizzled receptors in Drosophila. Science 288:1825-8.

• Boutros M., Paricio, N., Strutt, D., Mlodzik, M. (1998). Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94:109-18.