University of Heidelberg
BIOQUANT

Publications

2016

  • Graw F, Perelson AS: Modeling viral spread. Annu Rev Virol. 2016 3:555-72.
  • Dahari H, Canini L, Graw F, Uprichard SL, Araujo ES, Penaranda G, Coquet E, Chiche L, Riso A, Renou C, Bourliere M, Cotler SJ, Halfon P: HCV kinetic and modeling analyses indicate similar time to cure among sofosbuvir combination regimens with daclatasvir, simeprevir or ledipasvir. J Hepatol. 2016, 64:1232-9 doi:10.1016/j.hep.2016.02.022.
  • Kumberger P, Frey F, Schwarz US, Graw F: Multiscale modeling of virus replication and spread. FEBS Letters 2016, 590:1972-86.

2015

  • Madelain V, Oestereich L, Graw F, Nguyen TH, de Lamballerie X, Mentre F, G√ľnther S, Guedj J: Ebola virus dynamics in mice treated with favipiravir. Antiviral Res. 2015, doi:10.1016/j.antiviral.2014.08.015.
  • Garcia V, Richter K, Graw F, Oxenius A, Regoes RR: Estimating the in vivo killing efficacy of cytotoxic T lymphocytes across different peptide-MHC complex densities. PLoS Computational Biology 2015, 11(5):e1004178.
  • Graw F, Martin DN, Perelson AS, Uprichard SL*, Dahari H*: Quantification of Hepatitis C virus cell-to-cell spread using a stochastic modeling approach. Journal of Virology 2015, 89:6551-61 (*these authors contributed equally)
  • Johnson S*, Bergthaler A*, Graw F*, Flatz L, Bonilla WV, Siegrist CA, Lambert PH, Regoes RR#, Pinschewer DD#: Protective efficacy of individual CD8+ T cell specificities in chronic viral infection. Journal of Immunology 2015, 194:1755-62. (*,# these authors contributed equally)

2014

  • Graw F, Balagopal A, Kandathil AJ, Ray SC, Thomas DL, Ribeiro RM, Perelson AS: Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes. PLoS Computational Biology 2014, 10(11):e1003934.
  • Graw F, Regoes RR: Predicting the impact of CD8+ T cell polyfunctionality on HIV disease progression. J Virol 2014, 88(17): 10134-45
  • Bastidas S, Graw F, Smith MZ, Kuster H, G√ľnthard HF, Oxenius A: CD8+ T cells are activated in an antigen-independent manner in HIV infected individuals. Journal of Immunology 2014, 192:1732-44

2013

  • Seich al-Basatena NK, Chatzimichalis K, Graw F, Frost SDW, Regoes RR, Asquith B: Can non-lytic CD8+ T cells drive HIV-1 escape?PLoS Pathogens 2013, 9(11):e1003656
  • Kandathil AJ, Graw F, Quinn J, Hwang HS, Torbenson M, Perelson AS, Ray SC, Thomas DL, Ribeiro RM, Balagopal A: Use of lase capture microdissection to map HCV-positive hepatocytes in human liver. Gastroenterology 2013, 145:1404-1413

2012

  • Graw F, Weber KS, Allen PM, Perelson AS: Dynamics of CD4+ T cell responses against Listeria monocytogenes. Journal of Immunology 2012, 189:5250-5256
  • Graw F, Leitner T, Ribeiro RM: Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: Injecting drug users sustain the heterosexual epidemic in Latvia. Epidemics 2012, 4(2):104-116
  • Graw F, Regoes RR: Influence of the fibroblastic reticular network on cell-cell interactions in lymphoid organs. PLoS Computational Biology 2012, 8(3):e1002436

2011

  • Liu P, Overman RG, Yates NL, Alam SM, Vandergrift N, Chen Y, Graw F, Freel SA, Kappes JC, Ochsenbauer C, Montefiori DC, Gao F, Perelson AS, Cohen MS, Haynes BF, Tomaras GD: Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute and chronic HIV-1 infection. Journal of Virology 2011, 85(21):11196-11207
  • Haas A, Zimmermann K, Graw F, Slack E, Rusert P, Ledergerber B, Bossart W, Weber R, Thurnheer MC, Battegay M, Hirschel B, Vernazza P, Patuto N, Macpherson AJ, Gunthard HF, Oxenius A, the Swiss HIV Cohort Study: Systemic antibody responses to gut commensal bacterai during chronic HIV-1 infection. Gut 2011, 60(11):1506-1519
  • Graw F, Richter K, Oxenius A, Regoes RR: Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection. Proceedings of the Royal Society - B 2011, 278(1723):3395-3402

2010

  • Graw F*, Magnus C*, Regoes RR: Theoretical analysis of the evolution of immune memory. BMC Evolutionary Biology 2010, 10:380 (* these authors contributed equally)
  • Haas A, Rehr M, Graw F, Rusert P, Bossart W, Kuster H, Trkola A, Gunthard HF, Oxenius A: HIV-1 replication activates CD4+ T cells with specificities for persistent herpes virus. EMBO Molecular Medicine 2010, 2(6):231-244

2009

  • Graw F, Regoes RR: Investigating CTL mediated killing with a 3D cellular automaton. PLoS Computational Biology 2009, 5(8):e1000466
  • Graw F, Gerds  TA, Schumacher M: On pseudo-values for regression analysis in competing risks models. Lifetime Data Analysis 2009, 15(2):241-255

2007

  • Yates A, Graw F, Barber DL, Ahmed R, Regoes RR, Antia R: Revisiting estimates of CTL killing in vivo. PLoS ONE 2007, 2(12)

 

Books and contributed book chapters

  • Graw F, Perelson AS: Spatial aspects of HIV infection, contributed book chapter, Mathematical Methods and Models in Biomedicine, 2012, Springer
Contact: E-Mail (Last update: 12/11/2016)