University of Heidelberg
BIOQUANT

Conferences

Oct. 1-2, 2018: BIOMS-Conference 2018

Oct. 6-7, 2017: 3rd Workshop on Virus Dynamics

Oct. 9-10, 2017: Hengstberger-Symposium on Systems Immunology & Vaccine Design

Research:

Why does our immune system work the way it works? How does it actually work? And what is the reason that our immune system fails to work sufficiently against some types of infectious pathogens?

In our group, we are combining mathematical models and experimental data to understand fundamental immunological and virological processes that occur within a host in response to infection. We are particularly interested in the spatio-temporal dynamics of infection and immune processes, and how these dynamics determine the outcome of an infection or the efficacy of therapeutic interventions. Thereby, we especially aim at determining how single-cell behaviour shapes cell population dynamics. To this end, we develop mathematical methods and computational tools to analyse and understand how pathogens spread within different tissue environments, and how our immune system is able to memorize previous infections. 



Below you find an enumeration of specific topics and projects that we are currently working on in close collaboration with several experimental groups. These projects address open questions on specific aspects of host-pathogen interactions for different pathogens (such as HIV, HCV, Malaria and Ebola) and on the generation of immunological memory.

 

(1.) Pathogen dynamics and spread in complex environments

(2.) Immune cell differentiation and migration

(3.) Methods development

Contact: E-Mail (Last update: 01/01/2019)