We are interested in studying how viruses interact with cellular membranes and lipids during infection.  Many enveloped viruses such as influenza or Ebola must cross the cell membrane during entry and exit. To do so, viruses developed or hijacked fascinating protein machineries, which are able to remodel, fuse or cut membranes in processes dependent on specialized lipids. We use and further develop cryo-electron microscopy (cryo-EM) techniques such as cryo-focused ion beam milling (cryo-FIB), in situ cryo-electron tomography (cryo-ET) and cryo-correlative light and electron microscopy (cryo-CLEM) in conjunction with other imaging methods as fluorescence microscopy and imaging mass spectrometry to solve the puzzle of viral-membrane interactions.