University of Heidelberg


BioQuant website is relaunching soon! Please keep in mind that not all content on the current website may be up to date.


Corona: When planning a meeting in BioQuant's seminar rooms, please check the hygiene plans, number of participants and regulations on collecting contact details here.

Research Highlights

Microcensus in bacteria – Systems biology research reveals that bacteria can perform ratio-sensing.



More or better? Systems biology research provides insight into life cycle strategies of sporulating bacteria.





BIOQUANT building

BioQuant, the Center for “Quantitative Analysis of Molecular and Cellular Biosystems” at Heidelberg University was established in 2007 as an interdisciplinary University research center that is solely dedicated to research and training in systems biology.

In the meantime, the center has evolved into a successful platform for the development and constant refinement of mathematical models of complex biological systems as well as the swift validation of scientific hypotheses via experimental data.

BioQuant’s remarkable architecture ideally promotes scientific communication and interdisciplinary research at the interface between mathematics, experimental life sciences, and technology development & application. Currently, 30 theoretical and experimental research groups are affiliated with BioQuant. Their research activities cover multiple aspects of systems biology and focus on cellular processes with an emphasis on medically relevant topics e.g. gene regulation & repair, cellular signaling, immune biology, cell mechanics & adhesion, and cancer biology.

BioQuant hosts several technology platforms for systematic functional & quantitative imaging and single-cell sequencing-based methods combined with extensive IT capacity.

The imaging systems range from high-resolution microscopy, high-throughput and high-content live cell imaging to cryo-electron microscopy. The NIKON Imaging Center and the Hamamatsu TIGA (Tissue Imaging and Analysis) Center are both integral parts of BioQuant`s technology platforms.

Teaching Program for Systems Biology

BIOQUANT building

At Heidelberg University the entire teaching activities in systems biology are carried out in the context of the BioQuant Center. 

In the international Master’s program “Molecular Biosciences” at Heidelberg University, a new major curriculum for systems biology was established in 2008. The program covers fundamental topics in bioinformatics, computational analysis, network reconstruction, and dynamic pathway analysis as well as multi-scale modeling.

Systems Biology students at Heidelberg University profit from small classes and individual mentoring. Lectures provide a theoretical foundation, tutorials teach problem-solving skills. Lab rotations as well as master´s thesis are performed within the research groups of the teaching faculty. Thus, from an early stage on, students are integrated into cutting-edge systems biology research projects.

An international student exchange program with the Universities of Amsterdam, Luxembourg, Gothenburg, Manchester, and Tokyo Medical and Dental University offers students the opportunity to gain international experience during research internships at the participating systems biology centers.

For further information and application forms visit:

Most recently, the Research Training Group ''Mathematical Modelling for the Quantitative Biosciences’’ has been launched at BioQuant. For the first time, Heidelberg University offers a structured curriculum in systems biology at the PhD level. This program focuses on applying modelling, analysis, and simulation methods to biological systems at different levels of abstraction-from gene regulation to cell populations.


Save the date

BioQuant Seminar

After a long break, the BioQuant Seminar series is back! Find out more about the upcoming talks here.

Tuesday November 09, 4 pm via Zoom - Hosted by Ulrike Engel


Prof. Dr. Olivier Pertz

(Institute of Cell biology, University of Bern)

"Multiscale mechanisms of MAPK signaling robustness"


BioQuant Internal Seminar

Thursday July 29, 1 pm via Zoom

Stefan Kallenberger

"Model-based optimization of drug concentration trajectories"


Martin Zauser

"Analysis and modeling of calcium signatures in plants"

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Contact: E-Mail (Last update: 28/07/2021)