BioQuant Groups Biostatistics for Omics Data Prof. Dr. Simon Anders We develop methods to process, analyse and interpret high-throughput sequencing data. Complex Adaptive Traits (CATs) Dr. Ilka Bischofs We use tools from molecular biology, microscopy and mathematical modeling to control and engineer CATs. Membrane Biology of Viral Infection Dr. Petr Chlanda We are studying how viruses interact with cellular membranes and lipids during infection. High-Content Analysis of the Cell (HiCell) Dr. Holger Erfle We design, develop and apply novel technologies for high-content screening and analysis. Tissue Imaging & Analysis Center (TIGA) Apl. Prof. Dr. Niels Grabe We perform quantitative analysis and modeling of tissues, with emphasis on clinically relevant research projects. Modeling Infection & Immunity Dr. Frederik Graw We combine mathematical models and experimental data to study infection and immune processes within a host. Virus-Host Interactions Prof. Dr. Dirk Grimm We develop gene therapies by engineering non-pathogenic Adeno-associated viruses. Biomedical Genomics Dr. Carl Herrmann We work on gene (de)regulation in diseases and methods for integration of large scale genomics datasets. Systems Medicine Dr. Dr. Stefan Kallenberger We investigate pathomechanisms of diseases to improve diagnostics and treatment protocols based on mathematical modeling. Modeling of Biological Processes Prof. Dr. Ursula Kummer We develop methods for the simulation, modeling and analysis of biochemical networks. Single-Cell Open Lab Dr. Jan-Philipp Mallm We focus on providing automated, high-throughput and multi-omic readouts tailored to cancer research. Governance of Emerging Technologies in Medical Research and Health Care Prof. Dr. Fruzsina Molnár-Gábor We conduct research in the areas of data protection law, medical law, and health law. Biological Information Processing Dr. Jürgen Pahle We analyse how living systems take up, process, store and transfer information. Chromatin Networks Prof. Dr. Karsten Rippe We analyze the dynamic organization of the (epi)genome in relation to gene expression and functional cell states. Biomedical Computer Vision (BMCV) PD Dr. Karl Rohr We develop methods for computer-based analysis of biological and medical images. Protein Evolution Prof. Dr. Rob Russell We investigate all aspects of protein structure, function and evolution, focusing on molecular interactions. Methods in Computational Systems Biology Dr. Sven Sahle We develop computational methods and software for modeling and analysis of biochemical reaction networks. Cryo Electron Microscopy Prof. Dr. Rasmus Schröder We study actin-myosin macromolecular motor systems using single particle analysis and electron cryo tomography. Groups with Projects at BioQuant Health Data Science Unit Prof. Dr. Roland Eils We provide medical informatics solutions to make patient data accessible for clinical research and education. Tumor Immunology Prof. Dr. Dirk Jäger We focus on translation of innovative therapeutic approaches into early clinical trials for the treatment of tumors. Adaptive Immunotherapy Prof. Dr. Niels Halama We develop tissue processing workflows and technologies for applications in solid tumor immunotherapy. Single-Molecule Super-Resolution Microscopy Prof. Dr. Mike Heilemann We study biomolecule structures using sub-diffraction-limit resolution imaging with single-molecule sensitivity. Systems Biology of Signal Transduction Prof. Dr. Ursula Klingmüller We elucidate molecular mechanisms that regulate cellular decisions and their impact at the tissue- and organ-levels. Physics of Complex Biosystems Prof. Dr. Ulrich Schwarz We develop a systems-level understanding of cell mechanics and adhesion. Molecular Mechanisms of Intracellular Trafficking Prof. Dr. Vytautė Starkuvienė We analyse how intracellular trafficking adapts to extracellular signals. Joint projects at Vilnius University and Erfle lab. ERC DECODE Signaling and Functional Genomics Prof. Dr. Michael Boutros We study cellular signaling networks with genetic / genomic approaches, focusing on Wnt and Wnt-interacting pathways. Quantitative Biology and Statistics Dr. Wolfgang Huber We develop and apply statistical methods for biotechnologies and then translate them into reusable tools. Stem Cell Biology Prof. Dr. Jan Lohmann We study the development of complex stem cells in plants using genetic, genomic and molecular approaches. Statistical Genomics and Systems Genetics Dr. Oliver Stegle We develop statistical and machine learning methods to decipher molecular variation across individuals, space, and time. ERC IndiGene Developmental Biology / Physiology Prof. Dr. Jochen Wittbrodt We study neuronal cell proliferation and differentiation in the developing, growing and regenerating eye and brain of fish. Associated Groups Applied Analysis and Modelling in Biosciences Prof. Dr. Anna Marciniak-Czochra We use mathematical models to analyze the dynamics of structure formation and self-organisation in cell systems. Retroviral and Influenza Virus (IAV) Biology Prof. Dr. Hans-Georg Kräusslich We study the formation and architecture of subviral complexes and their interaction with cellular structures. Systems Biomedicine Prof. Dr. Julio Saez-Rodriguez We study signaling network deregulation in various diseases by integrating multi-omics data into mathematical models.